Faculty profile

Dr. Azra Mehmood

Associate Professor Stem Cell Research Lab

Leads the Stem Cells Therapeutics and Regenerative Medicine group, pioneering cord-derived stem cell therapies for burns, diabetic wounds and osteoarthritis in Pakistan.

Associate ProfessorCEMB · University of the Punjab
9PhD students produced
13Publications reported
€125,000European Foundation grant

Profile

Regenerative Medicine Scientist, Stem Cell Researcher and Educator

Dr. Azra Mehmood completed her BSc (Hons) in Animal Husbandry from the University of Agriculture, Faisalabad, joining CEMB in 2004 as an MPhil research scholar before receiving her PhD in 2011 under an indigenous HEC scholarship. Her doctoral research on endothelial progenitor cells in diabetic heart failure established the first rat models of diabetes-induced cardiomyopathy in Pakistan. She conducted postdoctoral research at the University of Cincinnati's Stem Cells Research Group.

She and her PhD researchers were the first in Pakistan to optimise culture conditions for human cord tissue-derived stem cells, skin keratinocytes, fibroblasts, chondrocytes, lipoaspirate-derived cells, and skin fibroblast-derived iPSCs, developing disease models for burns, oxidative stress and hyperglycaemia. She now leads the Stem Cells Therapeutics and Regenerative Medicine group as Associate Professor.

She has developed constructs combining stem cells with chitosan, PRP gel and amniotic-membrane scaffolds for wound healing, and since 2018 has engaged in clinical trials of autologous lipoaspirate stem cells for skin regeneration. She has produced nine PhD students, several trained at institutions including Johns Hopkins, Harvard Medical School and the Wellcome-MRC Cambridge Stem Cell Institute.

Selected contributions

Science translated into capability

01

First-in-Pakistan cell culture protocols

Optimised culture conditions for cord tissue, keratinocyte, fibroblast, chondrocyte and iPSC-derived stem cells for the first time in Pakistan.

02

Clinical translation

Leading clinical trials of autologous lipoaspirate stem cells for skin regeneration since 2018.

03

International society membership

Member of the American Heart Association, Wound Healing Society and TERMIS.

04

Awards

PCST Research Productivity Award (2016-17), Wound Healing Society travel grant (2017), and multiple Punjab University Performance Evaluation Awards.

Research output

Selected publications

A selection of publications listed on the official CEMB faculty profile.

  1. 01
    2023 · International Journal of Biological Macromolecules

    Zinc oxide loaded chitosan-elastin-sodium alginate nanocomposite gel using freeze gelation for enhanced adipose stem cell proliferation and antibacterial properties

  2. 02
    2023 · Regenerative Therapy

    Priming with caffeic acid enhances the potential and survival ability of human adipose-derived stem cells to counteract hypoxia

  3. 03
    2022 · Cryobiology

    Priming of adipose-derived stem cells with curcumin prior to cryopreservation preserves their functional potency

  4. 04
    2022 · Biomaterials Advances

    Hydrogel patch with pretreated stem cells accelerates wound closure in diabetic rats

  5. 05
    2021 · Burns & Trauma

    Curcumin preconditioning enhances the efficacy of adipose-derived mesenchymal stem cells to accelerate healing of burn wounds

  6. 06
    2021 · Biochemical Pharmacology

    Vitamin E pretreated Wharton's jelly-derived mesenchymal stem cells attenuate CCl4-induced hepatocyte injury in vitro and liver fibrosis in vivo

  7. 07
    2020 · Life Sciences

    Curcumin preconditioned human adipose derived stem cells co-transplanted with platelet rich plasma improve wound healing in diabetic rats

  8. 08
    2020 · Regenerative Medicine

    Antioxidant pretreatment enhances umbilical cord derived stem cells survival in response to thermal stress in vitro

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