Faculty profile

Prof. Dr. Abdul Qayyum Rao

Professor Plant Biotechnology Lab

Molecular biologist and Plant Biotechnology Group lead pioneering CRISPR genome editing and edible vaccine technologies in cotton and other crops.

ProfessorCEMB · University of the Punjab
17Research grants secured (4 international, 13 national)
6Patents filed
8Cotton varieties commercialized
10+Publications reported

Profile

Plant Molecular Biologist, Genome Editor and Educator

Dr. Abdul Qayyum Rao completed an MSc in Botany from Bahauddin Zakariya University Multan, an M.Phil in Molecular Biology from CEMB, University of the Punjab, and a PhD in Molecular Biology from CEMB, University of the Punjab. From 2005-2006 he served as a visiting scientist at DSMZ Braunschweig, Germany, and from 2016-2018 he worked as a Humboldt Fellow at the Joseph Gottlieb Kölreuter Institut für Pflanzenwissenschaften at the Karlsruhe Institute of Technology, Germany.

He has headed the Plant Biotechnology section at CEMB since 2009 and was promoted to Professor in 2021. He established CRISPR/Cas genome editing technology at CEMB and pioneered its edible vaccine section targeting poultry diseases.

His research spans transgenic cotton resistant to biotic stresses, genome editing of crop plants via CRISPR/Cas to improve productivity and stress tolerance, and development of plant-based pharmaceuticals and edible vaccines. Work from his lab has been translated into commercially released Bt and herbicide-resistant cotton varieties and six patent filings.

Selected contributions

Science translated into capability

01

CRISPR genome editing

Established CRISPR/Cas genome editing technology at CEMB to improve crop traits and address biotic and abiotic stresses.

02

Edible vaccine pioneer

Pioneered CEMB's edible vaccine programme targeting major poultry diseases such as Newcastle disease and Avian Influenza.

03

Transgenic cotton development

Led development of double- and triple-gene Bt/herbicide-resistant cotton varieties (CEMB 33, CA12, CEMB 66, CEMB 100, CKC series) grown commercially in Pakistan.

04

Patents

Holds one granted patent and five pending applications covering transgenic cotton, edible vaccines, and CRISPR-based crop improvement.

05

International research training

Trained as a visiting scientist at DSMZ Braunschweig, Germany, and as a Humboldt Fellow at the Karlsruhe Institute of Technology.

06

Research funding leadership

Secured four international and thirteen national competitive research grants totaling over PKR 100 million and USD 0.261 million.

07

Awards and honors

Recipient of the Pakistan Academy of Sciences ZKS Gold Medal (2022), Humboldt Fellowship (2016-2018), and ICRA Young Researcher Award (2017).

Research output

Selected publications

A selection of publications listed on the official CEMB faculty profile.

  1. 01
    2023 · Planta

    Multiplex Cas9 based excision of CLCuV β-satellite and DNAA revealed reduction of viral load with asymptomatic cotton plants

  2. 02
    2023 · Acta Physiologiae Plantarum

    CRISPR/Cas9-mediated genome editing in diploid and tetraploid potatoes

  3. 03
    2023 · Journal of King Saud University – Science

    Production of Proinflammatory cytokines by expressing Newcastle disease vaccine candidate in corn

  4. 04
    2022 · Planta

    CRISPR/Cas-mediated knockdown of vacuolar invertase gene expression lowers the cold-induced sweetening in potatoes

  5. 05
    2022 · Plant Science

    Tissue specific expression of Bacterial cellulose synthase (Bcs) genes improves Cotton fiber length and strength

  6. 06
    2022 · Nature Scientific Reports

    Overexpression of the AGL42 gene in cotton delayed leaf senescence through downregulation of NAC transcription factors

  7. 07
    2021 · Plant Cell Reports

    Development of broad spectrum and sustainable resistance in cotton against major insects through combination of Bt and plant lectin genes

  8. 08
    2021 · Molecular Biology Reports

    Enhancing the resilience of transgenic cotton for insect resistance

  9. 09
    2021 · GM Crops and Food

    Transformation and evaluation of Broad-Spectrum insect and weedicide resistant genes in Gossypium arboreum (Desi Cotton)

  10. 10
    2020 · Nature Scientific Reports

    Constitutive expression of Asparaginase in G. hirsutum triggers insecticidal activity against B. tabaci

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